2021 Ford E-350 problems, complaints & recalls

2021 Ford E-350 recalls (6)

• Recall 25V793000Nov 17, 20257,046 vehicles
  ENGINE

  Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles that received an incomplete software update under recall 20V795. The engine cover may become excessively hot.

  Risk: Direct contact with certain areas of engine cover surface in the passenger compartment may increase the risk of injury or burns to the skin of the driver or front seat passenger.

  Remedy: Dealers will update the powertrain calibration for heat management under elevated idle conditions, free of charge. Owner notification letters were mailed January 7, 2026. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 25SC7. Vehicle Identification Numbers (VINs) involved in this recall will be searchable on NHTSA.gov beginning December 22, 2025.

• Recall 24V097000Feb 9, 202416,543 vehicles
  SERVICE BRAKES, HYDRAULIC:FOUNDATION COMPONENTS:HOSES, LINES/PIPING, AND FITTINGS · STEERING:HYDRAULIC POWER ASSIST:HOSE, PIPING, AND CONNECTIONS

  Ford Motor Company (Ford) is recalling certain 2021-2022 E-350 and E-450 vehicles equipped with dual rear wheels. An inadequate connection between the power steering pressure line and the brake hydroboost unit may result in a sudden loss of power steering fluid.

  Risk: A sudden loss of power steering fluid can result in a loss of power steering and power brake assist, increasing the risk of a crash.

  Remedy: Dealers will replace the power steering pressure line and the hydroboost jumper line, free of charge. Vehicles in this recall were previously recalled under 22V-089 and owners will need to have the new remedy completed even if their vehicle was remedied under the prior recall. Owner notification letters were mailed on June 21, 2024. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 24S07.

• Recall 22V089000Feb 16, 202244,219 vehicles
  SERVICE BRAKES, HYDRAULIC:FOUNDATION COMPONENTS:HOSES, LINES/PIPING, AND FITTINGS · STEERING:HYDRAULIC POWER ASSIST:HOSE, PIPING, AND CONNECTIONS

  Ford Motor Company (Ford) is recalling certain 2021-2022 E-350 and E-450 vehicles equipped with dual rear wheels. An inadequate connection between the power steering pressure line and the brake Hydroboost unit may result in a sudden loss of power steering fluid.

  Risk: A sudden loss of power steering fluid can result in a loss of power steering and power brake assist, increasing the risk of a crash.

  Remedy: Dealers will inspect the connection between the power steering lines and the Hydroboost unit, and replace the power steering lines, as necessary, free of charge. Owner notification letters were mailed on March 18, 2022. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 22S08.

• Recall 20V795000Dec 17, 202029,344 vehicles
  ENGINE

  Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles. The underside of the engine cover may have mispositioned insulation, allowing the cover to get excessively hot.

  Risk: Direct and continuous contact with certain areas of engine cover surface in the passenger compartment may increase the risk of injury or burns to the skin of the driver or front seat passenger.

  Remedy: Ford will notify owners, and dealers will inspect the engine cover for gaps between the rubber seal and the insulation. If gaps are present, the dealer will install engine cover insulation patches in the right hand and left hand inner lower corners of the engine cover. The dealer will also update the powertrain calibration for heat management under elevated idle conditions should a vehicle be equipped with SEIC or BCP, free of charge. The recall began February 15, 2021. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S73.

• Recall 20V175000Mar 23, 20202,871 vehicles
  ELECTRICAL SYSTEM:WIRING · ELECTRONIC STABILITY CONTROL (ESC) · SERVICE BRAKES, HYDRAULIC:ANTILOCK/TRACTION CONTROL/ELECTRONIC LIMITED SLIP

  Ford Motor Company (Ford) is recalling certain 2021 E-350 and E-450 vehicles. A wire harness in the rear of the vehicle may contact the vehicle frame, resulting in damage to the circuits that support the fuel pump and the anti-lock braking system (ABS).

  Risk: Damage to the fuel pump circuit in the wiring harness could result in an unexpected engine stall. Damage to the ABS wiring can lead to reduction of ABS functionality and a loss of roll stability control (RSC) functionality. These scenarios increase the risk of a crash.

  Remedy: Ford will notify owners, and dealers will inspect the wire harness for damage. If no damage is found, dealers will apply anti-abrasion tape over the area and ensure clearance to surrounding components. If damage is found, dealers will splice in new wire and apply anti-abrasion tape over the area and ensure clearance to surrounding components. All services will be performed free of charge. The recall began May 18, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S13.

• Recall 20V099000Feb 21, 2020319 vehicles
  POWER TRAIN:DRIVELINE:DIFFERENTIAL UNIT · POWER TRAIN:DRIVELINE:DRIVESHAFT

  Ford Motor Company (Ford) is recalling certain 2020 F-550 and 2021 E-350 and E-450 vehicles. The rear axle differential fluid may be below the minimum level, possibly resulting in a failure of the rear axle assembly and driveshaft separation.

  Risk: If the driveshaft separates, there may be a loss of drive, increasing the risk of crash. Additionally, if the parking brake is not applied, unintended vehicle movement can occur and increase the risk of injury or crash.

  Remedy: Ford will notify owners, and dealers will inspect the rear axle differential fluid level and adjust it, or replace the rear axle as necessary, free of charge. The recall began March 19, 2020. Owners may contact Ford customer service at 1-866-436-7332. Ford's number for this recall is 20S09.

NHTSA defect investigations

• RQ24003Opened Feb 27, 2024Closed May 11, 2026

  Loss of Power Brake/Steering Assist Post Recall 22V089 Inspection.

  The Office of Defects Investigation (ODI) opened Recall Query (RQ) 24003 on February 27, 2024, to evaluate the scope and remedy effectiveness of NHTSA recall 24V097. On February 16, 2022, Ford Motor Company (Ford) issued a safety recall, NHTSA recall 22V089, for certain 2021-2022 Ford E-350 and E-450 vehicles equipped with dual rear wheels. According to the filing, specific hydraulic lines could leak resulting in a sudden loss of power steering and power brake assist, increasing the risk of a crash. The remedy involved a dealer inspection of the lines and their replacement as necessary. Only v…

Recent 2021 Ford E-350 complaints

Excerpts of the newest owner complaints, lightly cleaned of personal details. Complaints are unverified owner reports.

1. Filed Sep 13, 2026NCEngine

   Engine misfire on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was delivered to Ford of Spartanburg (Ford dealership) for diagnosis. The vehicle is still out of service. Ford's diagnosis, Repair Order 593079, June 26, 2026: "WILL NEED TO REPLACE ALL SPARK PLUGS AND WIRES, WILL ALSO NEED TO REPLACED ALL COILS DUE TO MISFIRES ON ALMOST EVERY CYLINDER." The Ford service advisor wrote the same day: "The engine also has a misfire that is unrelated to…

   NHTSA complaint #11763935 · source
2. Filed Sep 13, 2026NCEngine

   Engine failure on a 2021 Ford E-350 cutaway, 7.3L V8, used for parcel delivery. The vehicle was taken out of service and has not run since. Two diagnoses, both in writing. ACME Mobile Service, July 27, 2026, at 152,760 miles: "Found the #5 cylinder is completely disabled and dropped out. Truck will need a new motor." Ford of Spartanburg (Ford dealership), Repair Order 595835, August 25, 2026: "FOUND ENGINE IS KNOCKING, WILL NEED TO REPLACE MOTOR." Ford quoted $16,000.82 for…

   NHTSA complaint #11763932 · source
3. Filed Nov 28, 2025MAEngine

   Engine failure at 78,172, excess wear to the camshaft lobes and valve tappet surface. We have had 22 failures. There was a recall -24B27 for 2021 and 2022 models year for idle oil pressure. Most vans had 70 to 80k on them by the time we received a letter. Some engine have been changed twice. Ford has a serious problem and is not acknowledging it. Please help! Montachusett Regional Transit Authority , Fitchburg MA 01420

   NHTSA complaint #11701901 · source
4. Filed Feb 17, 2025INEngine

   This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.

   NHTSA complaint #11643148 · source
5. Filed Feb 17, 2025INEngine

   This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.

   NHTSA complaint #11643144 · source
6. Filed Feb 17, 2025INEngine

   This is one of 4 of my 2021 ford econoline fleet vehicles purchased in 2021 that have had engine failure. I am one of many contractors in my area and others around the country who have had this issue with the same F59 engine. Ford has failed to issue a recall.

   NHTSA complaint #11643142 · source
7. Filed Aug 18, 2024ORBrakesSteering

   After hitting a very rough patch of interstate, our steering became very difficult. The driver thought that maybe we had a low tire, so looked for a place to pull over. We crested a hill, and there was an exit with a truck stop. As we attempted to slow for the exit, the driver discovered we had no brakes or power steering. Driver used the brakes on the trailer we were towing to slow us and bring us to a stop. Checked the brake fluid reservoir. It was empty. Bought more, but…

   NHTSA complaint #11609275 · source
8. Filed Jul 6, 202340,000 miFLBrakesSteering

   The contact owns a 2021 Ford E-350. The stated while driving into the driveway, the vehicle made an abnormal popping sound. The vehicle lost power steering functionality, and the brake pedal became spongy. Additionally, the contact stated that there was a trail of fluid in the driveway. The contact stated that upon opening the hood, he noticed that the brake line had fractured, and brake fluid was leaking inside the engine compartment. There was no further information…

   NHTSA complaint #11530672 · source

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Source: U.S. National Highway Traffic Safety Administration (NHTSA) Office of Defects Investigation public data, as of Oct 11, 2026. Complaints are submitted by owners and are not verified by NHTSA or by us; a complaint does not prove a defect exists. View this vehicle on NHTSA.gov Methodology