2006 Mercedes-Benz E350 problems, complaints & recalls

2006 Mercedes-Benz E350 recalls (4)

• Recall 24V874000Nov 19, 202433,456 vehicles
  VISIBILITY:SUN/MOON ROOF ASSEMBLY

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2001-2011 C-Class, CLK, E-Class, and CLS vehicles. Please see the recall report for a complete list of models and model years. The glass sunroof panel may not be properly secured and can detach.

  Risk: A detached sunroof panel can become a road hazard, increasing the risk of a crash.

  Remedy: Dealers will inspect and replace the sunroof panel as necessary, free of charge. Owner notification letters were mailed January 10, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of previous NHTSA recall number 22V-954. MBUSA's number for this recall is 2024120001/2/3.

• Recall 22V954000Dec 23, 2022131,653 vehicles
  VISIBILITY:SUN/MOON ROOF ASSEMBLY

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2001-2011 C-Class, CLK, E-Class, and CLS vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The glass sunroof panel may not be properly secured and may detach.

  Risk: A detached sunroof panel may become a road hazard, increasing the risk of a crash.

  Remedy: Dealers will inspect and replace the sunroof panel as necessary free of charge. Owner notification letters were mailed February 3, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. This recall expands NHTSA recall number 19V-918. MBUSA's numbers for this recall are 2023010004, 2023010005, and 2023010006.

• Recall 21V196000Mar 19, 202111,356 vehicles
  VISIBILITY:SUN/MOON ROOF ASSEMBLY

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2006-2007 C350, C230, C280, CLK350, E320CDI, E350 Wagon, E350, 2006 C55 AMG, CLK500, CLS500, CLS55 AMG, E500 Wagon, E500, E55 AMG, 2007 CLK550, CLS550, CLS63 AMG, E550, E63 AMG, and E63 Wagon AMG vehicles. The bonding between the glass panel and the sliding roof frame may deteriorate, possibly causing the glass panel to detach from the vehicle.

  Risk: A detached glass panel can separate from the vehicle and become a road hazard, increasing the risk of a crash.

  Remedy: MBUSA will notify owners, and dealers will inspect the glass panel bonding and replace the sliding roof, as necessary, free of charge. Owner letters were mailed May 7, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of recall number 19V-918. MBUSA's number for this recall is 2021040012.

• Recall 19V918000Dec 20, 2019747,928 vehicles
  VISIBILITY:SUN/MOON ROOF ASSEMBLY

  Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2001-2011 vehicles. The bonding between the glass panel and the sliding roof frame may deteriorate, possibly resulting in the glass panel detaching from the vehicle. For a full list of the affected models visit: https://static.nhtsa.gov/odi/rcl/2019/RMISC-19V918-4126.pdf

  Risk: A detached glass panel can separate from the vehicle and become a road hazard, increasing the risk of a crash.

  Remedy: MBUSA will notify owners, and dealers will inspect the glass panel bonding and replace the sliding roof, as necessary, free of charge. The recall began July 10, 2020. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2020040011.

NHTSA defect investigations

• EA13003Opened Mar 15, 2013Closed Dec 19, 2014

  Fuel Leakage From The Fuel Tank

  The Office of Defects Investigation (ODI) opened this investigation on January 23, 2012 as PE12-001 based on 20 consumer reports in model year (MY) 2003-2006 E55 AMG vehicles.Based on new reports in other E-Class vehicles, ODI upgraded the investigation to Engineering Analysis (EA) 13-003 on March 15, 2013, and expanded the scope to all E-Class vehicles through MY 2008.The complainants alleged a strong odor of gasoline fuel both inside and outside of their vehicle, particularly after refilling the fuel tank.Many of the complainants noted that the odor subsided or went away after driving some d…

• PE10017Opened May 14, 2010Closed Nov 24, 2010

  Driver Air Bag Circuit High Resistance

  Mercedes-Benz USA (MBUSA) has reported a high number of warranty claims for air bag warning lamp illumination due to a diagnostic fault code 9103 or 9123 indicating a high resistance in the driver's frontal air bag firing circuit.MBUSA's testing and evaluation have shown that this condition is the result of a faulty connector (specifically, improper wire crimp) but that it will not prevent proper deployment of the driver's frontal air bag.The faulty connector can cause the air bag circuit resistance levels to exceed the threshold that illuminates the air bag warning lamp, but they do not excee…

Recent 2006 Mercedes-Benz E350 complaints

Excerpts of the newest owner complaints, lightly cleaned of personal details. Complaints are unverified owner reports.

1. Filed Sep 23, 2026152,786 miARBrakesElectrical System

   The contact owns a 2006 Mercedes-Benz E-350. The contact stated that the sensotronic brake control warning was illuminated. The contact researched and found information about warranty coverage for 2006-2010 models with a 25-year warranty. The vehicle was taken to the dealer, who diagnosed that the main battery needed to be replaced but had not provided the repair. The vehicle was also taken to a certified mechanic who diagnosed that the brakes were failing and the computer…

   NHTSA complaint #11766341 · source
2. Filed Dec 3, 2025MSBrakesDriver Assistance & Safety Tech

   Mercedes Benz issued a recall and extended a warranty on its 2003-2005 E Class SBC braking systems (recall # [phone removed]) and extended the warranty to 25 years; the 2006 E Class models have the exact same SBC braking system but is not included in the recall. Mercedes needs to add the 2006 E Class models to recall # [phone removed]. My 2006 is experiencing the same SBC issues the 2003-2005 models are known to have but because my vehicle is 2006 it is not covered by the…

   NHTSA complaint #11702819 · source
3. Filed Oct 23, 2025180,000 miTXTowedBrakes

   The contact called on behalf of the owner of a 2006 Mercedes-Benz E350. The contact stated that while his mother was driving at an undisclosed speed and approaching a traffic light, the brake pedal was depressed; however, the brakes failed to function as intended. The brake pedal was depressed down to the floorboard. The contact's mother used the parking brake to stop the vehicle. The ABS warning light was illuminated. The vehicle was towed to the residence and then to an…

   NHTSA complaint #11695309 · source
4. Filed Oct 21, 202597,900 miOHVisibility & Wipers

   The contact's son owns a 2006 Mercedes-Benz E350. The contact stated that while his son was driving at an undisclosed speed, the sunroof detached and shattered on the roadway. The vehicle was not taken to the dealer or an independent mechanic. The vehicle was not repaired. After investigating the failure, the contact related the failure to NHTSA Campaign Number: 19V918000 (Visibility) and 22V954000 (Visibility); however, the VIN was included in the recalls, but the vehicle…

   NHTSA complaint #11694784 · source
5. Filed Aug 29, 2024MO1 injuredEngineAcceleration & Cruise ControlTransmission & Drivetrain

   The engine in these cars are defective and can cause serious harm due to a part that was put inside the motor made of plastic. There was a lawsuit but if you didn’t get in on it you losses out for not knowing. I was recently at Mercedes dealership to fix recalls and they brushed me off. The car can catch fire and I’m already experiencing engine failure after only owning the car for a year. They don’t care because it’s an old car but it’s still being sold to unsuspecting…

   NHTSA complaint #11611501 · source
6. Filed Mar 21, 2024149,000 miNVBrakes

   The contact owns a 2006 Mercedes-Benz E350. The contact stated while driving at 35 MPH, the vehicle would not stop when depressing the brake pedal. No warning lights were illuminated, however, the contact stated the entire instrument panel was illuminated in red. The vehicle was taken to a local independent mechanic where the vehicle's brake line, brakes, and rotors were replaced. The contact stated the failure recurred. The vehicle was driven to the contact's residence and…

   NHTSA complaint #11578703 · source
7. Filed Feb 5, 2024177,000 miTXTowedBrakes

   The contact owns a 2006 Mercedes-Benz E350. The contact stated that upon depressing the brake pedal, there was a beeping sound coming from the vehicle with a message stating "Stop, Reduced Braking Power, Depress Brake Pedal Fully" displayed on the instrument panel. The contact pulled over to shoulder of the road. Due to the failure, the vehicle was towed to the residence. The dealer was notified of the failure and the contact was informed that the vehicle was not covered…

   NHTSA complaint #11569912 · source
8. Filed Dec 30, 2023NYEngine

   Certain Mercedes-Benz models 2005- 2007 M272 V6 and M273 V8’s have faced or are facing issues regarding the balance sprocket in which drives the camshaft and crankshaft of the vehicle. Mercedes-Benz had made a decision to make certain engine components out of soft metals, when such metals are not adequate in handling the stress of the engine. In particular, in many cases, the balance sprocket was made with inadequate materials and gradually deteriorated to the point in which…

   NHTSA complaint #11562755 · source

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Source: U.S. National Highway Traffic Safety Administration (NHTSA) Office of Defects Investigation public data, as of Oct 11, 2026. Complaints are submitted by owners and are not verified by NHTSA or by us; a complaint does not prove a defect exists. View this vehicle on NHTSA.gov Methodology