2021 Mercedes-Benz CLS 450 problems, complaints & recalls

Updated from NHTSA data · How we count

Owners have filed 1 complaints with NHTSA about the 2021 Mercedes-Benz CLS 450, most often about wheels & tires. There are 8 recalls for this model year.

Complaints
1
Recalls
8
Crashes
0
Fires
0
Injuries
0
Median mileage
—
at time of problem

Key facts

  • Wheels & Tires is the most-reported problem area, named in 1 of 1 complaints (100%).
  • The 2021 Mercedes-Benz CLS 450 has 8 recalls on file.
  • It ranks 5th of 5 Mercedes-Benz CLS 450 model years by our severity-weighted complaint score (1st = worst).

2021 Mercedes-Benz CLS 450 problems by category

  • Wheels & Tires
    1 complaints

A complaint can mention more than one problem area, so categories add up to more than the total.

Most-reported components

Component (as filed with NHTSA)Complaints
Wheels1

2021 Mercedes-Benz CLS 450 recalls (8)

  • Recall 24V100000Feb 9, 202412,191 vehicles
    ELECTRICAL SYSTEM:WIRING

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 CLS450, E450, E450 All-Terrain, AMG E53, AMG GT43, AMG GT53, and 2021 AMG CLS53 vehicles. The 48-volt ground cable connection located in the engine compartment may not be tightened properly and may result in the ground cable overheating.

    Risk: An overheated ground cable increases the risk of a fire.

    Remedy: Dealers will inspect the 48-volt ground cable connection and repair it as necessary, free of charge. Owner notification letters were mailed March 22, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024MMNNNN.

  • Recall 22V733000Sep 30, 202219,968 vehicles
    ELECTRICAL SYSTEM:12V/24V/48V BATTERY

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2022 CLS450 Coupe and AMG E53, 2019-2021 AMG CLS53 Coupe, and 2021-2022 E450 vehicles. The 12-Volt battery in the trunk may not be properly secured, which, in the event of a crash, can cause electrical connection failure, disabling various safety features including, emergency call (eCall) system, electric seat adjustment, hazard warning lights, and automatic door locks.

    Risk: The inability to operate safety features (eCall system, hazard lights, electric seats, or automatic door locks) can increase the risk of injury during a crash.

    Remedy: Dealers will secure the 12V battery, free of charge. Owner notification letters were mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100009.

  • Recall 22V365000May 20, 2022242,722 vehicles
    COMMUNICATION: AUTO CRASH NOTIFICATION · ELECTRICAL SYSTEM:SOFTWARE

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.

    Risk: A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.

    Remedy: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.

  • Recall 21V527000Jul 12, 2021542 vehicles
    AIR BAGS:SENSOR:SIDE IMPACT

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles. The side crash sensor connectors may come loose, which could delay the activation of air bags and seatbelts during a side impact crash.

    Risk: Air bags and seatbelts that don't function as intended can increase the risk of injury during a crash.

    Remedy: Dealers will inspect and replace as necessary, the side impact crash sensors, free of charge. Owner notification letters were mailed on September 3, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021070032/33.

  • Recall 21V483000Jun 25, 20214,917 vehicles
    SEAT BELTS:REAR/OTHER:RETRACTOR

    Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles. The rear seat belt automatic locking retractors may deactivate early, which can prevent the child restraint system from securing properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard number 208, "Occupant Crash Protection."

    Risk: An unsecured child restraint system can increase the risk of injury during a crash.

    Remedy: Dealers will inspect, and replace as necessary, the rear seat belt assemblies, free of charge. Owners notified of the voluntary recall campaign by an interim letter on August 13, 2021. A final letter was mailed on September 24, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.

  • Recall 21V354000May 14, 2021343,191 vehicles
    BACK OVER PREVENTION: SENSING SYSTEM: CAMERA · ELECTRICAL SYSTEM:SOFTWARE

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles. Please refer to MBUSA's recall report for specific vehicle model details. The MBUX multimedia system software may cause the display to remain black, or reboot after startup. This could result in the rearview camera image not displaying properly. As such, these vehicles fail to comply with the requirements of Federal Motor Vehicle Safety Standard (FMVSS) number 111, "Rear Visibility."

    Risk: A backup camera that displays a blank image reduces the driver's rear view, increasing the risk of a crash or injury.

    Remedy: The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373. MBUSA's number for this recall is 2021050012.

  • Recall 21V230000Apr 1, 20218,634 vehicles
    AIR BAGS:SENSOR:OCCUPANT CLASSIFICATION · SEAT BELTS:PRETENSIONER · SEATS

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C-Class, E-Class, E-Class Coupe and Convertible, GLC, CLS, AMG GT 4-door Coupe and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. A faulty electrical contact within the seat position switch may prevent the driver and passenger air bags and seat belt force limiters from properly activating during a crash.

    Risk: Air bags and seat belts that do not perform properly in a crash can increase the risk of injury.

    Remedy: MBUSA will notify owners, and dealers will replace the seat position switches, free of charge. Owner letters were mailed May 21, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040016.

  • Recall 21V058000Feb 5, 20211,292,258 vehicles
    COMMUNICATION: AUTO CRASH NOTIFICATION · ELECTRICAL SYSTEM:SOFTWARE

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles. Please refer to the Part 573 report for specific vehicle model details. The software design of the communication module may fail to communicate the correct vehicle location for the emergency call system (eCall) in the event of a crash.

    Risk: Failure of the eCall system may result in emergency responders being dispatched to the wrong location, increasing the risk of injury following a crash.

    Remedy: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267. MBUSA's number for this recall is 2021020025.

Recent 2021 Mercedes-Benz CLS 450 complaints

Excerpts of the newest owner complaints, lightly cleaned of personal details. Complaints are unverified owner reports.

  1. Filed Jul 4, 2022AZWheels & Tires
    During a trip driving from Sedona to San Diego, the rear passenger side rim (Part No. 25740120007x23) (see Picture1) failed with a through crack on the shoulder opposite the spoke side (see Picture2). This led to the loss of air pressure in the tire. The tire pressure sensor did indicate a low pressure condition. Upon inspection of the rim, the only possible solution was to have it welded in order to continue the trip. When the rim was taken to the repair shop, three more…
    NHTSA complaint #11472277 · source

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Other 2021 Mercedes-Benz models

Source: U.S. National Highway Traffic Safety Administration (NHTSA) Office of Defects Investigation public data, as of Oct 10, 2026. Complaints are submitted by owners and are not verified by NHTSA or by us; a complaint does not prove a defect exists. View this vehicle on NHTSA.gov Methodology