2022 Mercedes-Benz S 500 4MATIC problems, complaints & recalls

2022 Mercedes-Benz S 500 4MATIC recalls (9)

• Recall 26V638000Oct 2, 202630,064 vehicles
  SERVICE BRAKES, HYDRAULIC:FOUNDATION COMPONENTS

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022-2025 S 500 4MATIC, Maybach S 580 4MATIC, Maybach S 680 4MATIC, S 580 4MATIC, 2023-2025 S 580 E 4MATIC, and 2024-2025 AMG S 63 E Performance vehicles. The front brake hoses may rupture and leak brake fluid.

  Risk: A brake fluid leak can extend the distance needed to stop the vehicle, increasing the risk of a crash.

  Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters are expected to be mailed November 27, 2026. Owners may contact MBUSA customer service at 1-800-367-6372. This recall expands previous NHTSA recall number 25V116. Vehicle Identification Numbers (VINs) involved in this recall became searchable on NHTSA.gov on October 9, 2026.

• Recall 25V116000Feb 24, 202520,339 vehicles
  SERVICE BRAKES, HYDRAULIC:FOUNDATION COMPONENTS

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.

  Risk: A brake fluid leak can extend the distance needed to stop the vehicle, increasing the risk of a crash.

  Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2025030007.

• Recall 23V880000Dec 21, 202379,676 vehicles
  FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.

  Risk: A loss of drive power can increase the risk of a crash.

  Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of NHTSA recall number 23V-445.

• Recall 23V445000Jun 26, 2023143,551 vehicles
  FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.

  Risk: A loss of drive power can increase the risk of a crash.

  Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

• Recall 22V935000Dec 16, 20221 vehicles
  STRUCTURE:INTERIOR PANELS:DASHBOARD

  Mercedes-Benz USA, LLC (MBUSA) is recalling one 2022 S 500 vehicle. The dashboard may be insufficiently attached, which can result in an improper front passenger air bag deployment in the event of a crash.

  Risk: Improper deployment of an air bag can increase the risk of injury.

  Remedy: Dealers will replace a portion of the dashboard, free of charge. The owner notification letter was mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023010001.

• Recall 22V194000Mar 28, 202212 vehiclesDo not drive
  POWER TRAIN:AXLE ASSEMBLY · SUSPENSION:SUBFRAME/MOUNTING BRACKET

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 S580Z, S500V, and S580V vehicles. The sub frame weld for the thrust arm on the rear axle carrier may have been improperly welded, causing the thrust arm to break and detach.

  Risk: A detached thrust arm can cause a sudden loss of vehicle control, or cause the vehicle to pull to one side during emergency braking, increasing the risk of a crash.

  Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will inspect the sub frame weld on the rear axle carrier and replace the rear axle carrier as necessary, free of charge. Owner notification letters were mailed April 8, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for the recall is 2022030028.

• Recall 22V189000Mar 25, 20228,396 vehicles
  STEERING: STEERING WHEEL/HANDLE BAR

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.

  Risk: Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.

  Remedy: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.

• Recall 21V00J000Dec 27, 20211,239 vehicles
  COMMUNICATION: AUTO CRASH NOTIFICATION · ELECTRICAL SYSTEM:SOFTWARE

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 EQS450, S500, and S580 vehicles. The communication module software may restrict or disable the emergency call system (eCall).

  Risk: A disabled eCall system would prevent a vehicle occupant from contacting emergency services through the call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.

  Remedy: The communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed February 23, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022010006.

• Recall 21V931000Nov 29, 2021227 vehicles
  ELECTRICAL SYSTEM:SOFTWARE

  Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 S580, 2022 EQS450, EQS580, and S500 vehicles with an active and connected Mercedes me connect account. The MBUX infotainment system might allow activation of the television and internet display while driving, causing a distraction for the driver.

  Risk: Driver distraction can increase the risk of a crash.

  Remedy: MBUSA has updated their computer server to correct the issue for most vehicles, free of charge. For vehicles that were not able to be updated remotely, dealers will provide the software update, free of charge. Owner notification letters were mailed January 25, 2022. Owners may contact MBUSA customer service at 1-800-367-6372.

Recent 2022 Mercedes-Benz S 500 4MATIC complaints

Excerpts of the newest owner complaints, lightly cleaned of personal details. Complaints are unverified owner reports.

1. Filed Jul 1, 2026GAWheels & Tires

   The factory upgrade 21 inch spoke wheels with Pirelli P-Zero low profile tires are averaging a blow out every 800 miles. 5 flats and 2 sidewall blisters in the last 10,000 miles. Pirelli P-Zero 255/35/R21 Front and 285/30/R21 Rear are all four available for inspection if you tell me to save them before I replace them. There have been thousands of complaints and law suits re this issue just in the last 5 years on mercedes cars with low profile tires; to Mercedes, Pirelli,…

   NHTSA complaint #11747686 · source
2. Filed Mar 31, 2025NYDriver Assistance & Safety TechAcceleration & Cruise Control

   The following pictures will again show the issues that I'm having while driving my 2022 S Class Mercedes, while using the cruise control on the Belt Parkway. It shows me stuck in traffic and, although I can only go 11 miles an hour while I’m stuck in traffic, the cruise control wants to push it to 80 mph, which is indeed VERY VERY DANGEROUS!! as you can well imagine. Also, as you can see in the second picture, I have the cruise control set to 39 MPH. I have been writing for…

   NHTSA complaint #11651654 · source
3. Filed Mar 27, 2025NYDriver Assistance & Safety TechAcceleration & Cruise Control

   Here we go again, while driving on a side road with a 20 mph school speed limit, the cruise control wants to SPEED UP to 60 mph!! WHAT IS IT GOING TO TAKE TO REMEDY THIS BEFORE I’M INVOLVED IN A SERIOUS ACCIDENT!!

   NHTSA complaint #11650963 · source
4. Filed Mar 23, 2025NYDriver Assistance & Safety TechElectrical SystemAcceleration & Cruise Control

   I leased my 2022 S 500, Mercedes Benz. on September 28, 2022 and after about a year, I have had issues with the large screen/radio and cruise control in the vehicle. All events are documented at the Rockville Centre, Long Island service center. I have made numerous complaints beginning in January of this year through emails and was assigned a case number with Mercedes Benz corporate which is 12240831. On numerous occasions, while using the cruise control set to 50 MPH, the…

   NHTSA complaint #11649962 · source
5. Filed Mar 17, 2025NYDriver Assistance & Safety TechElectrical SystemTransmission & Drivetrain

   as a loyal Mercedes Benz customer for the past 15 years, here I am writing to you for the fourth time since January 28th. of this year. My case number is [XXX]. I leased my 2022 S 500, VIN # [XXX] on [XXX] and after about a year, I have had issues with the large screen/radio in the vehicle. All events are documented with your Rockville Centre, Long Island service facility where the staff has been very helpful. On numerous occasions, while using the cruise control set to 50…

   NHTSA complaint #11648771 · source
6. Filed Sep 14, 2024CADriver Assistance & Safety TechElectrical System

   The car slams on the brakes for no reason. phantom braking. i have been tailgated because cars behind me - particularly on tye highway - think i’ve brake checked them (but it was the care slamming on the brakes). the door handles don’t open/deploy reliably. sometimes they work, sometimes they don’t. the touch screens are incredibly dangerous - especially when the system freezes or doesn’t work properly - which is often. there are almost no physical buttons. the system…

   NHTSA complaint #11614618 · source
7. Filed Jul 26, 2024CA2 injuredTowedWheels & Tires

   I have the 2022 S 500 with 21 inch mag spoke rims with Pirelli 255/35R21 tires on it which comes stock from Mercedes Benz. I have now been in almost 15 tires repair claims and 3 rim replacements because of how poorly Mercedes designed the rims then put a tire soon the car that cannot handle the weight of the car. I hit a pot hole and my whole tire blew out almost causing a severe crash. this is again the almost 15th time this has happened. I took the car to Mercedes Beverly…

   NHTSA complaint #11604807 · source
8. Filed Jun 3, 2024CABody & StructureOther / Unknown

   We're on our fifth windshield, and I'm concerned that there is some sort of structural issue. We've lived in the same area for more than 10 years and have never had this problem with any of our other cars, SUVs, or trucks. Sometimes, it sounds like a piece of sand has hit the windshield, and BOOM...another cracked windshield, but it always cracks on the driver's side. This isn't normal. Also, settings don't save to our profiles, and the backup warning signal doesn't work…

   NHTSA complaint #11592292 · source

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Source: U.S. National Highway Traffic Safety Administration (NHTSA) Office of Defects Investigation public data, as of Oct 10, 2026. Complaints are submitted by owners and are not verified by NHTSA or by us; a complaint does not prove a defect exists. View this vehicle on NHTSA.gov Methodology