2022 Mercedes-Benz S 580 4MATIC problems, complaints & recalls

Updated from NHTSA data · How we count

Owners have filed 25 complaints with NHTSA about the 2022 Mercedes-Benz S 580 4MATIC, most often about driver assistance & safety tech. There are 8 recalls for this model year.

Complaints
25
Recalls
8
Crashes
0
Fires
1
Injuries
0
Median mileage
5,000 mi
at time of problem

Safety warning: at least one recall for this vehicle tells owners not to drive it until it is repaired. Check your VIN at nhtsa.gov/recalls.

Key facts

  • Engine is the most-reported problem area, named in 8 of 25 complaints (32%).
  • Driver Assistance & Safety Tech (8) and brakes (7) follow.
  • Half of the complaints that list mileage happened before 5,000 mi.
  • Owners reported 0 crashes, 1 fire and 0 injuries.
  • The 2022 Mercedes-Benz S 580 4MATIC has 8 recalls on file, including at least one “do not drive” warning.
  • It has the most serious complaint record of all 4 Mercedes-Benz S 580 4MATIC model years we track.

2022 Mercedes-Benz S 580 4MATIC problems by category

  • Engine
    8 complaints
  • Driver Assistance & Safety Tech
    8 complaints
  • Brakes
    7 complaints
  • Electrical System
    5 complaints
  • Wheels & Tires
    5 complaints
  • Transmission & Drivetrain
    4 complaints
  • Suspension
    3 complaints
  • Fuel, Hybrid & EV Propulsion
    2 complaints
  • Steering
    1 complaints
  • Other / Unknown
    1 complaints
  • Body & Structure
    1 complaints
  • Seats & Seat Belts
    1 complaints
  • Visibility & Wipers
    1 complaints

A complaint can mention more than one problem area, so categories add up to more than the total.

Most-reported components

Component (as filed with NHTSA)Complaints
Service brakes7
Engine6
Forward collision avoidance: automatic emergency braking5
Electrical system5
Power train4
Suspension3
Forward collision avoidance: adaptive cruise control3
Tires3

When problems happen (mileage)

7Under 10k110k–30k130k–60k60k–100k100k–150k150k+
Mileage at the time of the problem, for 2022 Mercedes-Benz S 580 4MATIC complaints that list mileage.

2022 Mercedes-Benz S 580 4MATIC recalls (8)

  • Recall 26V638000Oct 2, 202630,064 vehicles
    SERVICE BRAKES, HYDRAULIC:FOUNDATION COMPONENTS

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022-2025 S 500 4MATIC, Maybach S 580 4MATIC, Maybach S 680 4MATIC, S 580 4MATIC, 2023-2025 S 580 E 4MATIC, and 2024-2025 AMG S 63 E Performance vehicles. The front brake hoses may rupture and leak brake fluid.

    Risk: A brake fluid leak can extend the distance needed to stop the vehicle, increasing the risk of a crash.

    Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters are expected to be mailed November 27, 2026. Owners may contact MBUSA customer service at 1-800-367-6372. This recall expands previous NHTSA recall number 25V116. Vehicle Identification Numbers (VINs) involved in this recall became searchable on NHTSA.gov on October 9, 2026.

  • Recall 25V116000Feb 24, 202520,339 vehicles
    SERVICE BRAKES, HYDRAULIC:FOUNDATION COMPONENTS

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 S 500, Maybach S 580 4MATIC, 2021-2023 S 580 4MATIC, 2022 S 680 4MATIC, and 2023 S 580e 4MATIC vehicles. The front brake hoses may rupture and leak brake fluid.

    Risk: A brake fluid leak can extend the distance needed to stop the vehicle, increasing the risk of a crash.

    Remedy: Dealers will replace the front brake hoses, free of charge. Owner notification letters were mailed April 25, 2025. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2025030007.

  • Recall 24V704000Sep 20, 202427,190 vehicles
    ENGINE AND ENGINE COOLING:ENGINE:ENGINE CONTROL MODULE (ECU/ECM):SOFTWARE

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 S580, and Maybach S580 vehicles. In the event of a mechanical failure in the engine Camtronic system, the engine control unit (ECU) software may cause the engine to overheat or stall.

    Risk: An engine stall can increase the risk of a crash. In addition, an engine that overheats can increase the risk of a fire.

    Remedy: Dealers will update the ECU software, free of charge. Owner notification letters were mailed on November 15, 2024. Owner notification letters will be mailed in phases, on November 15, 2024, January 10, 2025, and February 21, 2025. Owners can contact Mercedes-Benz Customer Service at 1-877-496-3691. MBUSA's number for this recall is 2024100007.

  • Recall 23V880000Dec 21, 202379,676 vehicles
    FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.

    Risk: A loss of drive power can increase the risk of a crash.

    Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of NHTSA recall number 23V-445.

  • Recall 23V445000Jun 26, 2023143,551 vehicles
    FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.

    Risk: A loss of drive power can increase the risk of a crash.

    Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

  • Recall 22V194000Mar 28, 202212 vehiclesDo not drive
    POWER TRAIN:AXLE ASSEMBLY · SUSPENSION:SUBFRAME/MOUNTING BRACKET

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 S580Z, S500V, and S580V vehicles. The sub frame weld for the thrust arm on the rear axle carrier may have been improperly welded, causing the thrust arm to break and detach.

    Risk: A detached thrust arm can cause a sudden loss of vehicle control, or cause the vehicle to pull to one side during emergency braking, increasing the risk of a crash.

    Remedy: Owners are advised not to drive their vehicles until the remedy has been performed. Dealers will inspect the sub frame weld on the rear axle carrier and replace the rear axle carrier as necessary, free of charge. Owner notification letters were mailed April 8, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for the recall is 2022030028.

  • Recall 22V189000Mar 25, 20228,396 vehicles
    STEERING: STEERING WHEEL/HANDLE BAR

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.

    Risk: Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.

    Remedy: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.

  • Recall 21V00J000Dec 27, 20211,239 vehicles
    COMMUNICATION: AUTO CRASH NOTIFICATION · ELECTRICAL SYSTEM:SOFTWARE

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022 EQS450, S500, and S580 vehicles. The communication module software may restrict or disable the emergency call system (eCall).

    Risk: A disabled eCall system would prevent a vehicle occupant from contacting emergency services through the call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.

    Remedy: The communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed February 23, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022010006.

Recent 2022 Mercedes-Benz S 580 4MATIC complaints

Excerpts of the newest owner complaints, lightly cleaned of personal details. Complaints are unverified owner reports.

  1. Filed Sep 9, 202618,000 miMIDriver Assistance & Safety TechSteeringTransmission & Drivetrain
    The contact owns a 2022 Mercedes-Benz S 580. The contact stated that while driving at an undisclosed speed, the messages "Active Brake Assist Functions Currently Limited - See Owner's Manual", "Risk of Vehicle Rolling Away - N Activated Manually No Automatic Change To P", "Service Required Do Not Change Transmission Position", and "Active Parking Assist And Parktronic Inoperative - See Owner's Manual" were displayed, and an unknown warning light was illuminated.…
    NHTSA complaint #11763035 · source
  2. Filed Apr 19, 2026FLBrakesEngineTransmission & Drivetrain
    Vehicle: 2022 Mercedes-Benz S580 The vehicle is experiencing a severe and violent drivetrain "jolt" or "push" during gear transitions, specifically when shifting from 5th to 6th gear at cruising speeds. On multiple occasions, the jolt was so forceful that passengers believed the vehicle had been rear-ended by another car. This behavior is unpredictable and creates a significant safety hazard, as it causes a sudden change in vehicle momentum while driving in traffic. The…
    NHTSA complaint #11732269 · source
  3. Filed Jan 22, 2026CABrakesDriver Assistance & Safety Tech
    On multiple occasions, after the vehicle had been parked and not driven for approximately five days or more, the automatic parking brake locked in place and would not release. I attempted standard methods to disengage the brake, including manual release procedures and lightly rocking the vehicle, without success. The only way to release the brake was to apply significant pressure to the accelerator while in reverse, which caused the brake to suddenly unlock. The first…
    NHTSA complaint #11712692 · source
  4. Filed Jan 6, 2026FLDriver Assistance & Safety TechElectrical System
    Was driving the car at 3:00 P.M. and all of a sudden thr dash display when total black out nothing on the display screen. Speed,fuel,turnning singles nothing total black out. Took it to the dealership to fix as this can and would be a life threathing at loss of life could and can happen in a traffic sistiution
    NHTSA complaint #11709116 · source
  5. Filed Dec 7, 2025NYBrakesSuspensionWheels & Tires
    Mercedes-Benz S580 equipped with 21-inch wheels has experienced numerous tire blowouts over the course of ownership — too many to count. The blowouts occurred during normal driving on typical roads. Several blowouts caused rim damage and created a dangerous situation, including moments where I nearly lost control of the vehicle. This appears to be a design defect involving the 21-inch wheel and low-profile tire configuration, which seems structurally inadequate for normal…
    NHTSA complaint #11703501 · source
  6. Filed Sep 15, 202555,000 miILEngine
    The contact owns a 2022 Mercedes-Benz S 580. The contact stated that while driving at an undisclosed speed, the check engine warning light illuminated and the engine stalled. The vehicle was taken to the dealer, where it was diagnosed with a failed CAM shaft solenoid. The contact was informed that the CAM shaft solenoid needed to be replaced. In addition, the contact was informed that the engine needed to be dismantled. The vehicle was not repaired. The manufacturer was made…
    NHTSA complaint #11687434 · source
  7. Filed Sep 10, 2025ILElectrical SystemEngineOther / Unknown
    Over ~3 years of ownership, the vehicle has experienced recurrent electrical and engine-management issues, resulting in 15+ service visits and ~100 cumulative days out of service at an authorized dealer. Patterns include: (1) electrical—keyless entry intermittently unresponsive, instrument cluster flickering/rebooting, multiple warning messages including a battery/electrical icon, HVAC/A/C becoming inoperative without cooling; and (2) powertrain/engine—check-engine light…
    NHTSA complaint #11686347 · source
  8. Filed Sep 10, 2025OHBody & StructureVisibility & Wipers
    Subject: Report of Spontaneous Sunroof Explosion - Mercedes S580 2022 Model Dear National Highway Traffic Safety Administration, I am writing to report a concerning incident that occurred on [XXX] at approximately [XXX] while I was driving my 2022 Mercedes S580 to work on [XXX] N. During my drive, I experienced a sudden, loud explosion within the vehicle. Initially, I believed it was either a gunshot or that I had been rear-ended. In a state of confusion, I quickly pulled…
    NHTSA complaint #11686338 · source

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Source: U.S. National Highway Traffic Safety Administration (NHTSA) Office of Defects Investigation public data, as of Oct 11, 2026. Complaints are submitted by owners and are not verified by NHTSA or by us; a complaint does not prove a defect exists. View this vehicle on NHTSA.gov Methodology