2022 Mercedes-Benz GLS 450 4MATIC problems, complaints & recalls

Updated from NHTSA data · How we count

Owners have filed 16 complaints with NHTSA about the 2022 Mercedes-Benz GLS 450 4MATIC, most often about transmission & drivetrain. There are 10 recalls for this model year.

Complaints
16
Recalls
10
Crashes
2
Fires
1
Injuries
0
Median mileage
25,100 mi
at time of problem

Key facts

  • Electrical System is the most-reported problem area, named in 4 of 16 complaints (25%).
  • Transmission & Drivetrain (4) and driver assistance & safety tech (4) follow.
  • Half of the complaints that list mileage happened before 25,100 mi.
  • Owners reported 2 crashes, 1 fire and 0 injuries.
  • The 2022 Mercedes-Benz GLS 450 4MATIC has 10 recalls on file.
  • It ranks 2nd of 5 Mercedes-Benz GLS 450 4MATIC model years by our severity-weighted complaint score (1st = worst).

2022 Mercedes-Benz GLS 450 4MATIC problems by category

  • Other / Unknown
    5 complaints
  • Electrical System · 1 crash
    4 complaints
  • Transmission & Drivetrain · 2 crashes
    4 complaints
  • Driver Assistance & Safety Tech
    4 complaints
  • Engine · 1 crash
    3 complaints
  • Acceleration & Cruise Control
    3 complaints
  • Fuel, Hybrid & EV Propulsion · 1 crash
    2 complaints
  • Brakes · 1 crash
    2 complaints
  • Wheels & Tires
    1 complaints
  • Visibility & Wipers
    1 complaints

A complaint can mention more than one problem area, so categories add up to more than the total.

Most-reported components

Component (as filed with NHTSA)Complaints
Unknown or other5
Electrical system4
Power train4
Engine3
Forward collision avoidance: automatic emergency braking3
Service brakes2
Fuel/propulsion system2
Vehicle speed control2

When problems happen (mileage)

1Under 10k10k–30k130k–60k60k–100k100k–150k150k+
Mileage at the time of the problem, for 2022 Mercedes-Benz GLS 450 4MATIC complaints that list mileage.

2022 Mercedes-Benz GLS 450 4MATIC recalls (10)

  • Recall 24V207000Mar 15, 2024116,020 vehicles
    ELECTRICAL SYSTEM:WIRING

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2023-2024 GLE 350, 2020-2024 GLE 450, 2020-2023 GLS 580, GLE 580, 2019-2023 GLS 450, 2021-2023 Maybach GLS 600, AMG GLS 63, 2021-2024 AMG GLE 53, AMG GLE 53 Coupe, and AMG GLE 63 S vehicles. A 48-Volt ground connection under the passenger seat may not be secured properly, resulting in the ground connection overheating.

    Risk: An overheated ground connection can increase the risk of a fire.

    Remedy: Dealers will inspect and tighten the 48-Volt ground connection as necessary, free of charge. Owner notification letters were mailed on May 3, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024040002.

  • Recall 24V118000Feb 16, 2024105,071 vehicles
    POWER TRAIN:AUTOMATIC TRANSMISSION:CONTROL MODULE:SOFTWARE

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2023 GLE 450 and GLS 450 vehicles. The transmission may not fully downshift in certain conditions, causing the engine to stall.

    Risk: An engine stall increases the risk of a crash.

    Remedy: Dealers will update the transmission control unit software, free of charge. Owner notification letters were mailed March 29, 2024. Owners may contact MBUSA customer service at 1-800-367-6372.

  • Recall 23V880000Dec 21, 202379,676 vehicles
    FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.

    Risk: A loss of drive power can increase the risk of a crash.

    Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of NHTSA recall number 23V-445.

  • Recall 23V445000Jun 26, 2023143,551 vehicles
    FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.

    Risk: A loss of drive power can increase the risk of a crash.

    Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

  • Recall 23V178000Mar 17, 202370,225 vehicles
    STRUCTURE:BODY

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2022-2023 GLE350, GLE450, GLE580, GLS450, GLS580, Maybach GLS600, AMG GLE53, AMG GLE63 S, and AMG GLS63 vehicles. The rear door window trim bars may detach from the vehicle while driving.

    Risk: Detached trim bars may cause a road hazard and increase the risk of a crash or injury.

    Remedy: Dealers will inspect and secure the rear window trim bars, as necessary, free of charge. Owner notification letters were mailed May 5, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of previous recall number 22V-680. MBUSA's number for this recall is 2023040011.

  • Recall 22V936000Dec 16, 202269 vehicles
    STEERING:CRITICAL FASTENERS

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 GLE350, GLE450, 2022 AMG GLE53, AMG GLE63, and GLS450 vehicles. The steering coupling locking screw may loosen and possibly detach from the steering gear, resulting in a loss of steering control.

    Risk: A loss of steering control can increase the risk of a crash.

    Remedy: Dealers will replace the steering coupling locking screw, free of charge. Owner notification letters were mailed January 27, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022120016.

  • Recall 22V732000Sep 30, 202259,574 vehicles
    SEATS:MID/REAR ASSEMBLY

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 AMG GLS63, 2020-2022 GLS450 and GLS580 vehicles. Due to a manufacturing error, the locks on the third-row seatbacks may fail in the event of a crash.

    Risk: A seat with a seatback lock failure may not properly restrain occupants, increasing the risk of injury during a crash.

    Remedy: Dealers will inspect and replace the third-row seatback, as necessary, free of charge. Owner notification letters were mailed November 18, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100011.

  • Recall 22V680000Sep 12, 2022161,000 vehicles
    STRUCTURE:BODY

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2022 GLE350, GLE450, GLS450, 2021-2022 AMG GLE53, 2020-2021 GLE580, GLS580, and 2021 GLE400e, AMG GLS63, AMG GLE63 S, and Maybach GLS600 vehicles. Due to a manufacturing error, the rear door window trim bars may detach.

    Risk: Detached trim bars may cause a road hazard and increase the risk of a crash or injury.

    Remedy: Dealers will inspect and secure the rear window trim bars, as necessary, free of charge. Owner notification letters were mailed November 1, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022090010.

  • Recall 22V365000May 20, 2022242,722 vehicles
    COMMUNICATION: AUTO CRASH NOTIFICATION · ELECTRICAL SYSTEM:SOFTWARE

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details. An error in the communication module's SIM card software can cause a mobile network connection failure, disabling the emergency call (eCall) system.

    Risk: A disabled eCall system would prevent a vehicle occupant from contacting the emergency services call center in an emergency, potentially delaying emergency responders and increasing the risk of injury.

    Remedy: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022. Owner notification letters will be mailed in phases, on July 8, 2022, May 17, 2024, July 29, 2024, and September 27, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's numbers are for this recall is 2022060005 and 2023110006.

  • Recall 22V231000Apr 8, 202221,306 vehicles
    ELECTRICAL SYSTEM:WIRING:INTERIOR/UNDER DASH

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2020-2022 GLE450, GLS450, 2021-2022 AMG GLE53, 2020-2021 GLE580, GLS580, 2021 AMG GLE63, Maybach GLS600 and AMG GLS63 vehicles. A ground cable bolt for the 48V ground connection under the front passenger seat may not be secured properly, which can cause the electrical cable to overheat.

    Risk: An overheated electrical cable can increase the risk of a fire.

    Remedy: Dealers will inspect and tighten the ground cable bolt, as necessary, free of charge. Owner notification letters were mailed July 8, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040017.

Recent 2022 Mercedes-Benz GLS 450 4MATIC complaints

Excerpts of the newest owner complaints, lightly cleaned of personal details. Complaints are unverified owner reports.

  1. Filed Oct 1, 2026FLFuel, Hybrid & EV PropulsionOther / UnknownTransmission & Drivetrain
    The vehicle suffered a total internal transfer case mechanical failure at 22,909 miles, which was documented during a factory-scheduled Service B check. The dealership attempted a fluid flush, which immediately resulted in an active 4MATIC system failure warning on the dashboard. Complete mechanical failure of this 4MATIC component causes extreme drivetrain binding and wheel hopping during low-speed maneuvers, presenting a major vehicle control hazard and a high risk of…
    NHTSA complaint #11768362 · source
  2. Filed Sep 14, 2026WIBrakes
    I am writing to formally log an urgent Safety-Critical Incident Report regarding a complete brake system failure on my 2022 Mercedes-Benz GLS450 (VIN: ⁠[XXX]). Incident Details: Date & Time:[XXX] Vehicle Mileage: Approximate 30k miles Occupants: 5 family members (including 3 children) Maintenance History: Fully and regularly maintained according to manufacturer schedules. What Happened: While driving with my family on the highway, the brake pedal suddenly went completely…
    NHTSA complaint #11763973 · source
  3. Filed May 15, 2026NJDriver Assistance & Safety Tech
    I have been receiving errors that visibility is reduced. Lane departure system is not working and car has brake suddenly in moderate traffic despite not being close to vehicle ahead of me.
    NHTSA complaint #11738195 · source
  4. Filed Apr 16, 202650,000 miAZVisibility & Wipers
    The contact owns a 2022 Mercedes-Benz GLS450. The contact stated that while driving at an undisclosed speed, there was an abnormally loud sound coming from the roof of the vehicle. The vehicle was pulled over to the shoulder lane and the contact discovered that the sunroof glass had shattered. No warning lights were illuminated. A dealer was contacted, and the dealer suggested that the insurance provider be contacted. The vehicle was not diagnosed or repaired. The…
    NHTSA complaint #11731633 · source
  5. Filed Mar 17, 2026TXDriver Assistance & Safety Tech
    Car has been auto braking even though there is nothing in front of the car. This is extremely dangerous and could lead to serious rear end collisions. There are many similar complaints on online forums and Mercedes (and their lawyers) do nothing. Link to video: [XXX] INFORMATION REDACTED PURSUANT TO THE FREEDOM OF INFORMATION ACT (FOIA), 5 U.S.C. 552(B)(6)
    NHTSA complaint #11724974 · source
  6. Filed Jan 16, 2026NYFireOther / Unknown
    The vehicle caught fire while parked and running in the driveway of my home. There were no modifications, no accident, and no external cause. The fire occurred without warning and posed a serious safety risk to occupants and property. The vehicle was under manufacturer warranty at the time of the incident. The fire caused damages to my house too. There were no warning lamps or messages. Benz has not done an investigation yet.
    NHTSA complaint #11711487 · source
  7. Filed Jun 10, 2025VADriver Assistance & Safety TechAcceleration & Cruise Control
    The car has on 5+ occasions had the collision avoidance system shut down (photos of dash showing this are available and have been shared with the dealer). There were no weather incident at the time. Lane following........ same type of thing also shared with dealer. Most disturbing is on multiple occasions, with the speed control engaged driving on the interstate at 65 to 70 mph, the speed limit indicator on the dash changed to 40 (no speed limit change) and the car went into…
    NHTSA complaint #11665997 · source
  8. Filed Dec 28, 2024GACrashTowedEngineFuel, Hybrid & EV PropulsionTransmission & Drivetrain
    Vehicle lost power while driving on a busy freeway and came to a complete stop and would not restart resulting in it being struck by a vehicle in the rear. More information available in the collision center pre estimate scan and full estimate.
    NHTSA complaint #11632849 · source

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Source: U.S. National Highway Traffic Safety Administration (NHTSA) Office of Defects Investigation public data, as of Oct 10, 2026. Complaints are submitted by owners and are not verified by NHTSA or by us; a complaint does not prove a defect exists. View this vehicle on NHTSA.gov Methodology