2022 Mercedes-Benz E 450 problems, complaints & recalls

Updated from NHTSA data · How we count

Owners have filed 11 complaints with NHTSA about the 2022 Mercedes-Benz E 450, most often about electrical system. There are 5 recalls for this model year.

Complaints
11
Recalls
5
Crashes
0
Fires
0
Injuries
0
Median mileage
400 mi
at time of problem

Key facts

  • Electrical System is the most-reported problem area, named in 4 of 11 complaints (36%).
  • Fuel, Hybrid & EV Propulsion (3) and wheels & tires (2) follow.
  • Half of the complaints that list mileage happened before 400 mi.
  • The 2022 Mercedes-Benz E 450 has 5 recalls on file.
  • It ranks 4th of 6 Mercedes-Benz E 450 model years by our severity-weighted complaint score (1st = worst).

2022 Mercedes-Benz E 450 problems by category

  • Electrical System
    4 complaints
  • Fuel, Hybrid & EV Propulsion
    3 complaints
  • Wheels & Tires
    2 complaints
  • Brakes
    2 complaints
  • Steering
    1 complaints
  • Engine
    1 complaints
  • Driver Assistance & Safety Tech
    1 complaints
  • Body & Structure
    1 complaints
  • Transmission & Drivetrain
    1 complaints

A complaint can mention more than one problem area, so categories add up to more than the total.

Most-reported components

Component (as filed with NHTSA)Complaints
Electrical system4
Wheels2
Fuel system, gasoline2
Service brakes2
Structure:body1
Power train1
Engine1
Steering1

When problems happen (mileage)

1Under 10k10k–30k30k–60k60k–100k100k–150k150k+
Mileage at the time of the problem, for 2022 Mercedes-Benz E 450 complaints that list mileage.

2022 Mercedes-Benz E 450 recalls (5)

  • Recall 24V100000Feb 9, 202412,191 vehicles
    ELECTRICAL SYSTEM:WIRING

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 CLS450, E450, E450 All-Terrain, AMG E53, AMG GT43, AMG GT53, and 2021 AMG CLS53 vehicles. The 48-volt ground cable connection located in the engine compartment may not be tightened properly and may result in the ground cable overheating.

    Risk: An overheated ground cable increases the risk of a fire.

    Remedy: Dealers will inspect the 48-volt ground cable connection and repair it as necessary, free of charge. Owner notification letters were mailed March 22, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2024MMNNNN.

  • Recall 23V880000Dec 21, 202379,676 vehicles
    FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2024 GLE, GLS, C-Class, E-Class, S-Class, SL, GLC, CLS, AMG GT, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, causing a loss of drive power.

    Risk: A loss of drive power can increase the risk of a crash.

    Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 28, 2024. Owner notification letters will be mailed in phases, on February 23, 2024, April 19, 2024, June 28, 2024, August 9, 2024, October 1, 2024, and December 2, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. This recall is an expansion of NHTSA recall number 23V-445.

  • Recall 23V445000Jun 26, 2023143,551 vehicles
    FUEL SYSTEM, GASOLINE:DELIVERY:FUEL PUMP

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details. The fuel pump may shutdown, which can result in a loss of drive power.

    Risk: A loss of drive power can increase the risk of a crash.

    Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

  • Recall 22V733000Sep 30, 202219,968 vehicles
    ELECTRICAL SYSTEM:12V/24V/48V BATTERY

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2022 CLS450 Coupe and AMG E53, 2019-2021 AMG CLS53 Coupe, and 2021-2022 E450 vehicles. The 12-Volt battery in the trunk may not be properly secured, which, in the event of a crash, can cause electrical connection failure, disabling various safety features including, emergency call (eCall) system, electric seat adjustment, hazard warning lights, and automatic door locks.

    Risk: The inability to operate safety features (eCall system, hazard lights, electric seats, or automatic door locks) can increase the risk of injury during a crash.

    Remedy: Dealers will secure the 12V battery, free of charge. Owner notification letters were mailed January 20, 2023. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022100009.

  • Recall 22V189000Mar 25, 20228,396 vehicles
    STEERING: STEERING WHEEL/HANDLE BAR

    Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel. Due to a software error in the hand detection control unit, the hands-off detection might not detect when the driver's hands are away from the steering wheel when using the Active Distance Assist DISTRONIC system.

    Risk: Deactivated hands-off detection will prevent DISTRONIC system features from functioning, including warnings to grab the steering wheel and calling first responders as part of the Active Emergency Stop Assist, which can increase the risk of a crash or injury.

    Remedy: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022040010.

Recent 2022 Mercedes-Benz E 450 complaints

Excerpts of the newest owner complaints, lightly cleaned of personal details. Complaints are unverified owner reports.

  1. Filed Mar 16, 2026TNWheels & Tires
    When turning the steering to maximum wheel camber, the wheel rims roll over the sidewall of the OEM low-profile Pirelli tires, damaging the tires and causing bubbling in the sidewall. This happens at a negligible speed, such as exiting a parking space. This vehicle is 3+ years old with 15k miles. Low-profile tires appear to be incompatible with the steering design.
    NHTSA complaint #11724597 · source
  2. Filed Dec 9, 2024PAElectrical SystemTransmission & Drivetrain
    Twice within a year a "48 voltage battery malfunction" warning appeared on my dashboard. Then a red warning light appears and I had about 30 seconds to find a safe place to pull over as loss of power causes deceleration of the vehicle . The cause, according to the diagnostic test performed by 2 different Mercedes dealerships, is that a software update is needed. A know of no situation where the machine crashes first then you're told to update its software. I am concerned…
    NHTSA complaint #11629635 · source
  3. Filed Aug 31, 2024ALBody & Structure
    An underbody splash shield (one of three, I believe), covering the transmission (the middle of the three) detached at highway speed and fell off the vehicle. This caused the leading edge of another shield to detach, which then, due to air flow, began dragging the highway. It was quite a noise; initially I thought it was a tire blow out. I quickly decelerated to try to move to an exit (it was urban highway with no shoulders), at lower speeds, the panel stopped dragging. There…
    NHTSA complaint #11611928 · source
  4. Filed Nov 11, 2023CAFuel, Hybrid & EV Propulsion
    there is a recall on my vehicle for over 4 months now. i keep going/contacting the local dealers about the issue and they keep telling me to come back in a month and every time they tell me there is no remedy yet and they dont know when exactly they will be able to fix it. and according to NHTSA this could increase the risk of crash or injury. please help me either get this fixed or make sure its safe for me to drive. thank you
    NHTSA complaint #11554671 · source
  5. Filed Sep 25, 2023FLFuel, Hybrid & EV Propulsion
    The contact owns a 2022 Mercedes Benz E450. The contact received notification of NHTSA Campaign Number: 23V445000 (Fuel System, Gasoline) however, the part to do the recall repair was not yet available. The local dealer was made aware of the issue and confirmed that parts were not yet available. The contact stated that the manufacturer had exceeded a reasonable amount of time for the recall repair. The manufacturer was made aware of the issue. The contact had not experienced…
    NHTSA complaint #11546319 · source
  6. Filed Sep 12, 2023NYFuel, Hybrid & EV Propulsion
    The contact owns a 2022 Mercedes-Benz E450. The contact received notification of NHTSA Campaign Number: 23V445000 (Fuel System, Gasoline) however, the part to do the recall repair was unavailable. The contact stated that the manufacturer had exceeded a reasonable amount of time for the recall repair. The manufacturer was not made aware of the issue. The contact had not experienced a failure. VIN tool confirms parts not available.
    NHTSA complaint #11544097 · source
  7. Filed May 18, 2023400 miPAElectrical SystemEngine
    The contact owns a 2020 Mercedes-Benz E450. The contact stated that on three occasions the driver's side front seat independently adjusted when the vehicle was started. On another occasion, the vehicle started by independently. Additionally, the head-up projected display moved up the windshield instead of remaining in place. The contact stated that the battery warning light was illuminated. The contact stated that on several occasions the vehicle stalled. The vehicle was…
    NHTSA complaint #11522705 · source
  8. Filed Oct 3, 2022CABrakesElectrical System
    I was driving the car on a road I drive daily with my son in a child seat in the back row. The car inexplicably slammed on the brakes at full force, stopping in time to avoid driving over the shadow of a tree. Approximately thirty minutes later, there was a loud popping / explosion sound from inside the engine compartment, the car lost all power, coasted along for approximately 100 feet, and then restarted while coasting. This is the second time in under a year that the car…
    NHTSA complaint #11487625 · source

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Source: U.S. National Highway Traffic Safety Administration (NHTSA) Office of Defects Investigation public data, as of Oct 11, 2026. Complaints are submitted by owners and are not verified by NHTSA or by us; a complaint does not prove a defect exists. View this vehicle on NHTSA.gov Methodology